The best advice for a fulfilled life: "learn how to learn". This from a marvelous story told by Andrei Alexandrescu, about how a few words, in a minute of conversation, can change a life radically.

For what is worth, Andrei's and my country of birth and education seemed to have a rather consistent and solidly planted attitude towards learning, that could be distilled exactly to this: learn how to learn. I distinctly remember my lyceum and my university professors saying exactly these words to us. And teaching by example too.